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The Acceptable Daily Intake (ADI) is the amount of a food additive that can be ingested daily with the diet, even during a lifetime, without an appreciable health risk on the basis of all facts known at the time.
Basically the ADI values are established by scientific expert committees that advise national and international regulatory authorities:
- In the European Union the "Scientific Committee on Food" (SCF) is responsible
- On an international level the Joint Expert Committee on Food Additives (JECFA, a body within the Food and Agriculture Organisation (FAO) of the United Nations/World Health Organisation)
To determine an ADI all available toxicological data from scientific studies is reviewed. The maximum dietary level of the additive that is without demonstrable toxic effects is called the "No Observable Effect Level" (NOEL). This level is then adjusted by inclusion of a large safety factor - often 100 - providing a large margin of safety.
The ADI values are recommendations and do not have legal status. They are taken into consideration during the rulemaking process by the legislator.

Overview of the ADI value of sweeteners (mg/kg body weight)

Intense SweetenerADI Values
Acesulfame K15
Neohespiridine DC5
Thaumatinenot specified

(Values according to JECFA-evaluation)

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